Day 1 – Wednesday, January 22, 2020
7:00-8:00 Career Mentoring: Women in Infectious Disease Research (Event Space, Includes light breakfast)
Natasha Kirienko, PhD, Assistant Professor, Rice University
Barbara Wells Trautner, MD, PhD, Professor and Director, Baylor College of Medicine
Helen Boucher, MD, Professor, Tufts Medical Center
8:00-8:30 Registration and light breakfast
8:30-8:35 Welcome
Cesar Arias, MD, PhD, Professor, University of Texas Health Science Center
8:35-9:00 Drowning of the Antibiotic Pipeline: How to Save it
Helen Boucher, MD, Professor, Tufts Medical Center
Session 1
Conveners: William Miller, MD, Assistant Professor, University of Texas Health Science Center
Adriana Rosato, PhD, Associate Professor, Houston Methodist Research Institute
9:00-9:25 Cell Envelope of Gram-Negative Bacteria: An Antibacterial Target
Anna Konovalova, PhD, Assistant Professor, University of Texas Health Science Center
9:25-9:50 Antibiotic Resistance and the Gonococcus: Regulation of Gene Expression
William Shafer, PhD, Professor, Emory University
9:50-10:15 Emergence of Antibiotic Resistance in Streptococci
Anthony Flores, MD, PhD, Associate Professor, University of Texas Health Science Center
10:15-10:45 Break and Vendor Show
Session 2
Conveners: Jourdan Andersson, PhD, Postdoctoral Associate, Baylor College of Medicine
Luis Vega, PhD, Postdoctoral Research Fellow, University of Texas Health Science Center
10:45-11:10 Antivirulence Approaches Against Pseudomonas aeruginosa
Natasha Kirienko, PhD, Assistant Professor, Rice University
11:10-11:35 Mining Fungal Genomes for Concealed Natural Product Antimicrobials
Gerald Bills, PhD, Professor, University of Texas Health Science Center
11:35-12:00 Revisiting Therapeutics Against MDR Gram-negative Bacteria
David Greenberg, MD, Associate Professor, University of Texas Southwestern
12:00 Pick up lunches (Event Space)
12:30-1:00 Rapid Fire Session (Event Space)
Samuel Aitken, MDACC, Microbiome and cumulative antibiotic use as predictors of Stenotrophomonas maltophilia infection in patients with acute myeloid leukemia receiving remission-induction chemotherapy , Poster #1
Amira Bhalodi, Accelerate Diagnostics, Inc., Improving Outcomes and Antibiotic Stewardship for Patients with Bloodstream Infections (IOAS): A Quasi-Experimental Multicenter Analysis of Time to Optimal Therapy, Poster #4
Larissa Grigoryan, BCM, Effectiveness of Antibiotic Stewardship Intervention for Urinary Tract Infections in Primary Care: a Difference in Differences Study, Poster #10
Jinhee Jo, UH, A Single-Center Surveillance Study of Cystic Fibrosis Microbiological Culture, Poster #13
Heer Mehta, RU, Evolution of Resistance to Doxycycline and Ciprofloxacin in the Category A Bioterrorism Agent, Francisella tularensis, Poster #18
Christine Pybus,UT Southwestern, Cefiderocol Retains Anti-Biofilm Activity in Gram-Negative Pathogens, Poster #24
David Reynoso, UTMB, A User-Friendly Qliksense® Application To Track & Report Essential Stewardship Metrics, Poster #25
1:00-2:00 Poster session and lunch (Event Space) Poster Numbers 1-32
Session 3
Conveners: Andrew Chou, MD, Assistant Professor, Baylor College of Medicine
Barbara W. Trautner, MD, PhD, Professor, Baylor College of Medicine
2:00-2:25 Non-antibiotic Host-targeted Therapeutics and Antimicrobial Peptides to Combat Multiple Drug Resistant Microbes
Ashok Chopra, PhD, Professor, University of Texas Medical Branch
2:25-2:50 Antibiotic Resistance in Clostridium difficile Drives the Need for Alternate Therapeutic Strategies
Julian Hurdle, PhD, Associate Professor, Texas A&M Health Science Center
2:50-3:15 Emergence Resistance Against New β-lactam/β-lactamase Inhibitors: Epidemiology and Mechanisms
Ryan Shields, PharmD, Associate Professor, University of Pittsburgh
3:15-3:30 Break
Session 4
Conveners: Truc T. Tran, PharmD, Assistant Professor, University of Texas Health Science Center
Yousif Shamoo, PhD, Professor and Vice-Provost for Research, Rice University
3:30-3:55 Toward Understanding how Positive Supercoiling Drives Fluoroquinolone Efficacy
Lynn Zechiedrich, PhD, Professor, Baylor College of Medicine
3:55-4:20 Leveraging Regulation and Genetic Bases of Ceftaroline Resistance in MRSA: Role of Carbapenems
Adriana Rosato, PhD, Associate Professor, Houston Methodist Research Institute
4:20-4:45 Cell Membrane Changes Associated with Daptomycin Resistance
Brian Werth, PharmD, Associate Professor, University of Washington
4:45-5:10 Microbiome and Worsening Glycemia Among Mexican Americans in Starr County, Texas
Eric Brown, PhD, Associate Professor, University of Texas Health Science Center
5:10-5:25 Selected abstract
Genetic and Phenotypic Signatures Predictive of ‘Bicarbonate [NaHCO3]-Responsiveness’ and β-Lactam Sensitization Among Methicillin-Resistant Staphylococcus aureus (MRSA)
Selvi Ersoy, University of California Los Angeles
5:25-5:40 Selected abstract
Emergence of Unusual Carbapenemase-producing Carbapenem Resistant Organisms in Houston, Texas
Ifrah Chaudhary, Houston Health Dept.
Day 2 – Thursday, January 23, 2020
Translational and Clinical Aspects of Antibiotic Resistance
7:00-8:00 Career Mentoring: Meet the Professors Basic Scientist Track (Event Space, Includes light breakfast)
Ashok Chopra, PhD, Professor, University of Texas Medical Branch
Lynn Zechiedrich, PhD, Professor, Baylor College of Medicine
Tim Palzkill, PhD, Professor, Baylor College of Medicine
8:00-8:30 Registration and light breakfast
Session 5
Conveners: William Miller, MD, Assistant Professor, University of Texas Health Science Center
Luis Ostrosky-Zeichner, MD, Professor, University of Texas Health Science Center
8:30-8:55 Catheter Associated Bloodstream Infections and Resistance
Isaam Raad, MD, Professor, University of Texas MD Anderson Cancer Center
8:55-9:20 Clinical Impact of Antibiotic Resistance in Pediatric Infections
Sheldon Kaplan, MD, Professor, Texas Children’s Hospital
9:20-9:45 New Insights into the Development of Carbapenem Resistance in Non-carbapenemase Producing Enterobacteriaceae
Sam Shelburne, MD, PhD, Professor, University of Texas MD Anderson Cancer Center
9:45-10:15 Vendor Show and Networking
Session 6
Conveners: Norma Perez, DO, Associate Professor, University of Texas Health Science Center
Jennifer Walker, PhD, Assistant Professor, University of Texas Health Science Center
10:15-10:40 The Carbapenem-resistant Enterobacteriaceae Epidemic in the United States
David van Duin, MD, PhD, Associate Professor of Medicine, University of North Carolina
10:40-11:05 Antibiotic Use and Prevention of Resistance
Sara Cosgrove, MD, Professor, Johns Hopkins Medicine
11:05-12:00 Keynote: The Interaction Between the Immune System and Antimicrobials
Victor Nizet, MD, PhD, Professor and Vice-Chair for Basic Research, University of California San Diego
12:00 Lunch (pick up lunches and be seated for rapid fire session)
12:30-1:00 Rapid Fire Session (Event Space)
Sam Erickson, UTHSCH, The YxdJK System is a Targeted Stress Response that Mediates Specific Protection Against the Human Antimicrobial Peptide LL-37 in Enterococcus faecalis, Poster #42
Ravikanthreddy Marreddy, Texas A&M IBT, Antimicrobial Mode of Action of Ebselen Against Clostridium difficile, Poster #52
April Nguyen, UTHSCH, Cardiolipin Synthase Mediates Daptomycin Resistance in Enterococcus faecalis, Poster #53
Rudo Simeon, Texas A&M, Engineering Protease-Stable DARPin Inhibitors of Clostridium Difficile Toxin B, Poster #58
Doris Taylor, BCM, Use of a DNA-Encoded Chemical Library Approach to Identify Inhibitors For Use of a DNA-Encoded Chemical Library Approach to Identify Inhibitors For, Poster #61
Jessica Galloway-Pena, MDACC, Oral and Stool Microbiome Community Coalescence is Driven by Antibiotic Exposure in Acute Leukemia Patients, Poster #66
1:00-2:00 Poster session and Lunch (Event Space) Poster Numbers 33-68
Session 7
Conveners: Cesar Arias, MD, PhD, Professor, University of Texas Health Science Center
2:00-3:00 Challenging Clinical Cases on Antimicrobial Resistance
Vance Fowler, MD, Professor, Duke University
David van Duin, MD, PhD, Associate Professor, University of North Carolina
Luis Ostrosky-Zeichner MD, Professor, University of Texas Health Science Center
3:00-4:00 T32 Trainee Symposium: Texas Medical Center Training Program on Antimicrobial Resistance (TP-AMR) and Emory Training Program on Antimicrobial Resistance
Conveners: Lynn Zechiedrich, PhD, Professor, Baylor College of Medicine
Kevin Garey, PharmD, Professor, University of Houston
3:00-3:15 Association of Antimicrobial Resistance-encoding Mobile Genetic Elements with Enhanced Bacterial Pathogen Fitness and Transmissibility
Luis Vega, PhD, Postdoctoral Research Fellow, University of Texas Health Science Center
3:15-3:30 Utilizing Host Targeted, Immunomodulating Drugs to Combat Clostridioides Difficile Infection
Jourdan Andersson, PhD, Associate Fellow, Baylor College of Medicine
3:30-3:45 Aminoglycoside Heteroresistance in Gram-Negative Pathogens
Edgar Sherman, Graduate Student, Emory University
Session 8 Microbiome session: Sponsored by the Kelsey Research Foundation
Conveners: Herbert Dupont, MD, Professor, University of Texas Health Science Center
Blake Hanson, PhD, Assistant Professor, University of Texas Health Science Center
4:00-4:25 Microbiome Changes and Clinical Outcomes in Bone Marrow Transplant Patients
Ying Taur, MD, MPH, Infectious Disease Specialist, Memorial Sloan Kettering Cancer Center
4:25-4:50 Role of the Microbiome in Modulating Bacterial and Fungal Bloodstream Infections
Andrew Koh, MD, Associate Professor, University of Texas Southwestern
4:50-5:35 Keynote: Superbugs and The Gut Microbiome
Cynthia Sears, MD, Professor, Johns Hopkins University
Day 3 – Friday, January 24, 2020
Antibiotic Stewardship
7:00-8:30 Career Mentoring: Meet the Professors, Clinical Scientist Track, MDs and PharmDs (Event Space, Includes light breakfast)
Edward Septimus, MD, Professor, Harvard Medical School and Texas A&M College of Medicine
Trish M. Perl MD, Professor, University of Texas Southwestern
Vincent Tam, PharmD, Professor, University of Houston
8:00-8:30 Registration and light breakfast
Session 9
Convener: Charlene Offiong, PharmD, HAI Coordinator, Houston Health Department
8:30-8:35 Opening Remarks
Ed Septimus, MD, Professor, Harvard Medical School and Texas A&M College of Medicine
8:35-9:20 Keynote: Tennessee Experience
Christopher Evans, PharmD, BCPS, Pharmacist, Healthcare Associated Infections and Antimicrobial Resistance Program, Tennessee Department of Health
9:20-9:50 Sepsis Quality Measures: Balancing Timely Care, Antibiotic Stewardship, and Reliability
Chanu Rhee, MD, MPH, Assistant Professor, Harvard Medical School
9:50-10:20 Diagnostic Testing C. difficiles
Kevin Garey, PharmD, Professor, University of Houston College of Pharmacy
10:20-10:50 Vendor show and networking
Session 10
Conveners: Kristi Kuper, PharmD, Director of Clinical Pharmacy, TabulaRasa Healthcare/DoseMe
10:50-11:20 Transition of Care
Christy Su, PharmD, Clinical Pharmacy Specialist, Memorial Hermann Greater Heights
11:20-11:50 Penicillin Allergy Evaluation as Antibiotic Stewardship
Kimberly Blumenthal, MD, Assistant Professor, Harvard Medical School/Massachusetts General Hospital
11:50-12:20 Panel: Clinical Cases
Ed Septimus, MD, Professor, Harvard Medical School and Texas A&M College of Medicine
Sara Cosgrove, MD, Professor, Johns Hopkins Medicine
Lilian Abbo, MD, Professor, Jackson Health System and University of Miami Miller School of Medicine
12:20-1:05 Panel: Houston Stewardship Best Practices
Moderator: Frank Tverdek, PharmD, Clinical Pharmacy Manager, MD Anderson Cancer Center
Mandelin Cooper, PharmD, Director of Clinical Pharmacy, HCA Clinical Services Group
Chase Janak, PharmD, Clinical Specialist, Houston Methodist Hospital
Andrea L. Mora, PharmD, Clinical Associate Professor and Vice Chair, Texas A&M College of Pharmacy
1:05-2:30 Poster viewing and Lunch (Event Space)
Session 11
Conveners: Samuel Aitken, Pharm D, Clinical Pharmacy Specialist, MD Anderson Cancer Center
José Munita, MD, Associate Professor, Clinica Alemana, Universidad del Desarrollo, Chile
2:30-3:00 Organ Transplant Stewardship
Lilian Abbo, MD, Professor, Jackson Health System and University of Miami Miller School of Medicine
3:00-3:30 CAP Guideline Update
Daniel Musher, MD, Professor, Baylor College of Medicine
3:30-4:00 Immunization Panel Discussion
Carol Baker, MD, Professor, University of Texas Health Science Center
Flor M. Munoz-Rivas, MD, Associate Professor, Texas Children’s Hospital
Robert Atmar, MD, Professor, Baylor College of Medicine
4:00-4:15 Closing Remarks
Cesar Arias, MD, PhD, Professor, University of Texas Health Science Center